A brief history
England introduced routine MenB vaccination for babies in September 2015. It targets meningococcal group B, which is distinct from the A, C, W and Y groups covered by MenACWY. Neither vaccine prevents every cause of meningitis.
How does it spread?
Meningococci can be carried harmlessly in the throat and spread through close contact with saliva or respiratory secretions. Occasionally they enter the bloodstream and cause invasive disease.
Symptoms and possible complications
MenB can cause meningitis and sepsis that worsen quickly. Fever, unusual drowsiness, neck stiffness or a non-fading rash need urgent attention. Babies may feed poorly or be difficult to wake. Suspected meningitis or sepsis is an emergency: do not wait for every symptom or a rash.
Where it may be relevant
- Infants in the routine programme
- People with particular medical or occupational risk
- Individuals seeking private protection after an assessment
Dose schedules
The clinician will select the appropriate licensed schedule after reviewing age, health, previous doses and departure date.
Adult course
Adults and older children
Infant and young-child course
Age-dependent
The number and intervals vary substantially by age at the first dose.
Who may be eligible
- Adults and children from the selected product's licensed age
- People whose age and previous doses allow an appropriate course
Who may not be eligible
- Anyone with a confirmed severe allergic reaction to a previous dose or a vaccine ingredient
- People who are acutely unwell with a significant fever may need vaccination deferred
- Pregnancy, breastfeeding, immune suppression and current medicines must be reviewed individually
Potential side effects
- Pain, redness or swelling where the injection is given
- Headache, tiredness, muscle aches or a mild fever
- Feeling faint around the time of vaccination
- Fever is particularly common in young children
Important risks and precautions
- A severe allergic reaction is very rare and requires urgent treatment
- Protection is not absolute, so relevant food, water, bite or exposure precautions remain important
- The exact product and schedule must be confirmed during a clinical assessment
Clinical references