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Clearly explained.

Rotavirus vaccine

Rotavirus vaccine is a live oral vaccine that reduces severe rotavirus gastroenteritis in infants.

What is it?

Rotavirus causes vomiting and diarrhoea and can lead to dehydration, particularly in babies and young children.

Where it may be relevant

  • Infants eligible within the strict routine-programme age limits
  • Babies receiving doses through NHS childhood services

Dose schedules.

The clinician will select the appropriate licensed schedule after reviewing age, health, previous doses and departure date.

Routine infant course

Eligible infants

Dose 18 weeks
Dose 212 weeks

Strict upper age limits apply to both doses.

Who may be eligible

  • Infants young enough to start and finish the course within current age limits

Who may not be eligible

  • Anyone with a confirmed severe allergic reaction to a previous dose or a vaccine ingredient
  • People who are acutely unwell with a significant fever may need vaccination deferred
  • Pregnancy, breastfeeding, immune suppression and current medicines must be reviewed individually
  • Older children and adults are not eligible
  • Previous intussusception, severe combined immunodeficiency and some gastrointestinal conditions are contraindications

Potential side effects

  • Temporary stomach discomfort, nausea or diarrhoea
  • Headache or tiredness
  • An allergic reaction is possible but uncommon

Important risks and precautions

  • A severe allergic reaction is very rare and requires urgent treatment
  • Protection is not absolute, so relevant food, water, bite or exposure precautions remain important
  • The exact product and schedule must be confirmed during a clinical assessment
  • There is a very small increased risk of intussusception; urgent assessment is needed for severe abdominal pain, repeated vomiting or blood in stool

Clinical references

Further information.

Information is general and does not replace a personal assessment, prescribing decision or the latest destination-specific advice.

Frequently asked questions

What does the rotavirus vaccine protect against?

It reduces severe rotavirus diarrhoea in babies.

Who should consider the rotavirus vaccine?

It is an infant programme vaccine and is not offered to adults.

How many doses of the rotavirus vaccine are needed?

The routine oral course is given at 8 and 12 weeks within strict age limits.

Can I have the rotavirus vaccine close to departure?

Book an assessment even when departure is close. Whether vaccination can be completed or still provide useful protection depends on the product, previous doses and time available.

Can the rotavirus vaccine be given with other vaccines?

Many vaccines can be given at the same appointment, but spacing rules can apply to some live vaccines. The clinician will check the products, your history and the proposed schedule.